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Panama Canal & Central America Cruises

Cruise ship passing locks in the Panama Canal (Photo: Sorin Colac/Shutterstock)

About Panama Canal & Central America Cruises

A cruise on the Panama Canal through Central America can appeal to more than one type of passenger. The Panama Canal portion of the trip focuses on the transit itself,with onboard lectures as ships make their way through the locks. Within the rest of Central America, put on your hiking boots and head for the rainforest or kick off your shoes and hit the beach. Port highlights include Costa Rica's Puntarenas and Limon, with excursions that cater to adrenaline junkies.

  • More about the Panama Canal & Central America

  • What is the best time to cruise to the Panama Canal & Central America?

  • Which cruise lines go to the Panama Canal & Central America?

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We found you 191 cruises

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16 Nights

Transcanal Cruise

Port: San Francisco • Puerto Vallarta • Puerto Quetzal • Puntarenas • Fuerte Amador • +3 more

1,032 reviews
Sep 28, 2024
Princess Cruises
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20 Nights

Panama Canal

Port: Vancouver • Santa Barbara • San Diego • Puerto Vallarta • Huatulco • Puerto Chiapas • +5 more

1,210 reviews
Oct 6, 2024
Holland America Line
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Cruise Critic Favorite

23 Nights

Transcanal Cruise

Port: Vancouver • San Francisco • San Diego • Santa Barbara • Los Angeles • Puerto Vallarta • +7 more

1,032 reviews
Oct 21, 2025
Princess Cruises
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Azamara Journey
Azamara Journey
Azamara Journey Cabins
Azamara Journey
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Azamara Journey
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Azamara Journey
Azamara Journey
Azamara Journey

9 Nights

Transcanal Cruise

Port: Fuerte Amador • Panama Canal • Puerto Limon • Roatan • Santo Tomas de Castilla • Costa Maya • +2 more

840 reviews
Dec 13, 2024
Azamara
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21 Nights

Repo - Panama Canal

Port: Seattle • San Francisco • Los Angeles • Cabo San Lucas • Puerto Vallarta • Manzanillo • +8 more

453 reviews
Oct 13, 2024
Norwegian Cruise Line
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15 Nights

Panama Canal - Miami

Port: Miami • Cartagena • Panama Canal • Panama City • Puerto Quetzal • Acapulco • Puerto Vallarta • +3 more

519 reviews
Nov 30, 2024
Norwegian Cruise Line
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16 Nights

Panama Canal Cruise

Port: Los Angeles • Pacific Ocean • Cabo San Lucas • Pacific Ocean • Acapulco • Pacific Ocean • +9 more

23 reviews
Jan 25, 2026
Regent Seven Seas Cruises
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21 Nights

Panama Canal

Port: Vancouver • San Francisco • San Diego • Cabo San Lucas • Puerto Vallarta • Huatulco • +6 more

974 reviews
Sep 29, 2024
Holland America Line
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16 Nights

Panama Canal

Port: San Diego • Puerto Vallarta • Huatulco • Puerto Chiapas • Puerto Quetzal • Puntarenas • +3 more

1,210 reviews
Oct 10, 2024
Holland America Line
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12 Nights

Transcanal Cruise

Port: Fort Lauderdale • Grand Cayman • Limon Bay • Panama Canal • Colon • Aruba • Curacao • +1 more

1,885 reviews
Dec 18, 2024
Princess Cruises
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16 Nights

Panama Canal Cruise

Port: Los Angeles • Ensenada • Pacific Ocean • Cabo San Lucas • Pacific Ocean • Acapulco • +10 more

119 reviews
Jan 24, 2025
Oceania Cruises
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16 Nights

Panama Canal Westward Cruise

Port: Fort Lauderdale • Grand Cayman • Cartagena • Colon • Panama Canal • Puerto Quetzal • +3 more

1,677 reviews
Apr 13, 2025
Royal Caribbean International
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16 Nights

Repo - Panama Canal

Port: Los Angeles • Cabo San Lucas • Puerto Vallarta • Acapulco • Puerto Quetzal • Panama City • +4 more

519 reviews
Jan 5, 2025
Norwegian Cruise Line
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25 Nights

Repo - Panama Canal

Port: Tampa • Cartagena • Colon • Panama Canal • Puntarenas • San Juan del Sur • Puerto Quetzal • +10 more

2,067 reviews
Apr 3, 2025
Norwegian Cruise Line
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21 Nights

Repo - Panama Canal

Port: Seattle • Victoria • San Francisco • Los Angeles • Cabo San Lucas • Acapulco • +6 more

519 reviews
Sep 29, 2025
Norwegian Cruise Line
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More about the Panama Canal & Central America

What is the best time to cruise to the Panama Canal & Central America?

Panama Canal and Central America cruise season is from October through April. The rainy season doesn't end until November, so cruises here are more popular from December onward. For more: Best Month to Cruise to the Panama Canal

Which cruise lines go to the Panama Canal & Central America?

Most major cruise lines, including Princess and Holland America, feature at least a few Panama Canal sailings in addition to expedition lines like Tauck and Lindblad. Cruisers can choose from a partial or full transit of the canal (Panama Canal: Partial Transit vs. Full Transit). Cruises that specifically explore countries like Costa Rica (without the canal) are on offer, from small-ship lines like Windstar Cruises.

What are some things to do in the Panama Canal & Central America?

In addition to either a full or partial crossing of the Panama Canal, most cruises in this region include stops in popular ports throughout Central America, Mexico and the Caribbean. That means you can do anything from lounge on the beach to explore ancient ruins or enjoy some duty-free shopping. If you can, trek Arenal Volcano from Puerto Limon, Costa Rica.

Do you need a passport to take a cruise to the Panama Canal & Central America?

Yes, a passport is required for travel throughout Central America, including Panama.

What should I pack for a cruise to the Panama Canal & Central America?

The weather in this region tends to be hot and humid, so pack plenty of shorts and t-shirts. Since Panama Canal crossings tend to be longer sailings, be prepared that your cruise might have more than one formal night.

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